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Index > Protein center > WISP2(Gene name) > Human
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  • WISP2 (Gene name),
  • WNT1-inducible-signaling pathway protein 2 (Protein name ),  WISP2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    WISP2(UNQ228/PRO261;CCN5;CT58;CTGFL);
    Protein name:
    WNT1-inducible-signaling pathway protein 2(WISP-2);
    Alternative:
    Connective tissue growth factor-like protein(CTGF-L);CCN family member 5;Connective tissue growth factor-related protein 58;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    250
    Sequence:
    50:
    MRGTPKTHLL | AFSLLCLLSK | VRTQLCPTPC | TCPWPPPRCP | LGVPLVLDGC | 
    100:
    GCCRVCARRL | GEPCDQLHVC | DASQGLVCQP | GAGPGGRGAL | CLLAEDDSSC | 
    150:
    EVNGRLYREG | ETFQPHCSIR | CRCEDGGFTC | VPLCSEDVRL | PSWDCPHPRR | 
    200:
    VEVLGKCCPE | WVCGQGGGLG | TQPLPAQGPQ | FSGLVSSLPP | GVPCPEWSTA | 
    250:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    SMR:
    UniGene:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human WISP-2
    Cat.:
    E2153m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human WISP-2
    Cat.:
    E2153h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human WISP-2
    Cat.:
    E2153r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human WISP-2
    Cat.:
    U2153h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human WISP-2
    Cat.:
    U2153r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human WISP-2
    Cat.:
    U2153m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human WISP-2
    Cat.:
    P2153Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human WISP-2
    Cat.:
    P2153Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human WISP-2
    Cat.:
    P2153Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human WISP-2
    Monoclonal Antibody for Human WISP-2
    Monoclonal Antibody for Human WISP-2
    Protein for Human WISP-2
    Protein for Human WISP-2
    Protein for Human WISP-2

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    References
    1. 1.
      "Identification and cloning of a connective tissue growth factor-like cDNA from human osteoblasts encoding a novel regulator of osteoblast functions."
      Kumar S. , Hand A.T. , Connor J.R. , Dodds R.A. , Ryan P.J. , Trill J.J. , Fisher S.M. , Nuttall M.E. , Lipshutz D.B. , Zou C. , Hwang S.M. , Votta B.J. , James I.E. , Rieman D.J. , Gowen M. , Lee J.C.
      J. Biol. Chem.274:17123-17131(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "CT58, a new member of the connective tissue growth factor family, interacts with the breast cancer associated mucin MUC1."
      Rowles J. , Gendler S.
      Submitted (1998-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors."
      Pennica D. , Swanson T.A. , Welsh J.W. , Roy M.A. , Lawrence D.A. , Lee J. , Brush J. , Taneyhill L.A. , Deuel B. , Lew M. , Watanabe C. , Cohen R.L. , Melham M.F. , Finley G.G. , Quirke P. , Goddard A.D. , Hillan K.J. , Gurney A.L. , more...
      Proc. Natl. Acad. Sci. U.S.A.95:14717-14722(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Lung.
    4. 4.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Skeletal muscle.
    6. 6.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Brain.
      tissue: Lung.
      tissue: Ovary.
    9. 9.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-38
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